Thromb Haemost 2002; 87(02): 345-346
DOI: 10.1055/s-0037-1612999
Letters to the Editor
Schattauer GmbH

The Impact of the Kozak Sequence Polymorphism of the Glycoprotein Ibα Gene on the Risk and Extent of Coronary Heart Disease

Sentot Santoso
1   Institut für Klinische Immunologic und Transfusionsmedizin
,
Peter Zimmermann
2   Institut für Klinische Chemie und Pathobiochemie, Justus-Liebig-Universität Gießen, Germany
,
Ulrich J. H. Sachs
1   Institut für Klinische Immunologic und Transfusionsmedizin
,
Andreas Gardemann
2   Institut für Klinische Chemie und Pathobiochemie, Justus-Liebig-Universität Gießen, Germany
› Author Affiliations
Further Information

Publication History

Received 25 November 2000

Accepted after resubmission 24 September 2001

Publication Date:
13 December 2017 (online)

 

 
  • References

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  • 2 Afshar-Khargan V, Li CQ, Khoshnevis-Asl M, Lopez JA. Kozak sequence polymorphism of the Glycoprotein (GP) Ibα gene is a major determinant of the plasma membrane levels of the platelet GPIb-IX-V complex. Blood 1999; 94: 186-91.
  • 3 Corral J, Lozano ML, Gonzalez-Conejero R. et al. A common polymorphism flanking the ATG initiator codon of GPIbα does not affect expression and is not a major risk factor for arterial thrombosis. Thromb Haemost 2000; 83: 23-8.
  • 4 Gardemann A, Mages P, Katz N, Tillmanns H, Haberbosch W. The p22 phox A640G gene polymorphism but not the C242T gene variation is associated with coronary heart disease in younger individuals. Atherosclerosis 1999; 145: 315-23.
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  • 6 Croft SA, Hampton KK, Daly ME, Steeds RP, Channer KS, Samani NJ. Kozak sequence polymorphism in the platelet GPIbα gene is not associated with the risk of myocardial infarction. Blood 2000; 95: 2183.
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