Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www-thieme-connect-de.accesdistant.sorbonne-universite.fr/rss/thieme/en/10.1055-s-00000020.xml
Download PDF
Geburtshilfe Frauenheilkd 2013; 73(8): 760-764
DOI: 10.1055/s-0033-1350706
DOI: 10.1055/s-0033-1350706
Aktuell diskutiert
Endokrinologie. Alternative Therapiemöglichkeiten zur Hormontherapie – Teil 2: pflanzliche Therapien, nicht hormonale Therapien und mehr
Further Information
Publication History
Publication Date:
27 August 2013 (online)
Alternative Therapiemöglichkeiten klimakterischer Beschwerden umfassen Nahrungsergänzungsmittel, nicht rezeptpflichtige, überwiegend pflanzliche Präparate und nicht hormonale Therapien mit Arzneimitteln anderer Indikationsbereiche. Präparate, die Cimicifuga racemosa oder Phytoestrogene beinhalten, werden am häufigsten eingesetzt. Zu diesen Präparaten liegen heute auch die meisten wissenschaftlichen Untersuchungen vor.
-
Literatur
- 1 Borelli F, Ernst E. Black cohosh (Cimicifuga racemosa) for menopausal symptoms: A systemic review of its efficacy. Pharmacol Res 2008; 58: 8-14
- 2 Kraft K. Cimicifuga, Johanniskraut und andere Phytotherapeutika im Klimakterium. Gynäkologische Endokrinologie 2008; 6: 72-75
- 3 Walji R, Boon H, Guns E et al. Black cohosh (Cimicifuga racemosa [L.] Nutt.): safety and efficacy for cancer patients. Support Care Cancer 2007; 15: 913-921
- 4 Leach MJ, Moore V. Black cohosh (Cimicifuga spp.) for menopausal symptoms. Cochrane Database Syst Rev 2012; (9) CD007244
- 5 Palacio C, Masri G, Mooradian AD. Black cohosh for the management of menopausal symptoms: a systematic review of clinical trials. Drugs Aging 2009; 26: 23-36
- 6 Cheema D, Coomarasamy A, El-Toukhy T. Non-hormonal therapy of post-menopausal vasomotor symptoms: a structured evidence-based review. Arch Gynecol Obstet 2007; 276: 463-469
- 7 Geller SE, Studee L. Botanical and dietary supplements for menopausal symptoms: what works, what does not. J Womens Health 2005; 14: 634-649
- 8 Huntley AL, Ernst E. A systematic review of the safety of black cohosh. Menopause 2003; 10: 58-64
- 9 Kronenberg F, Fugh-Berman A. Complementary and alternative medicine for menopausal symptoms: a review of randomised, controlled trials. Ann Int Med 2002; 137: 805-813
- 10 Newton KM, Reed SD, LaCroix AZ et al. Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo. Ann Intern Med 2006; 145: 869-879
- 11 Briese V, Stammwitz U, Friede M et al. Black cohosh with or without St. Johnʼs wort for symptom-specific climacteric treatment – results of a large-scale, controlled, observational study. Maturitas 2007; 57: 405-414
- 12 Laakmann E, Grajecki D, Doege K et al. Efficacy of Cimicifuga racemosa, Hypericum perforatum and Agnus castus in the treatment of climacteric complaints: a systematic review. Gynecol Endocrinol 2012; 28: 703-709
- 13 Hirschberg AL, Edlund M, Svane G et al. An isopropanolic extract of black cohosh does not increase mammographic breast density or breast cell proliferation in postmenopausal women. Menopause 2007; 14: 89-96
- 14 Raus K, Brucker C, Gorkow C et al. First-time proof of endometrial safety of the special black cohosh extract (Actaea or Cimicifuga racemosa extract) CR BNO 1055. Menopause 2006; 13: 678-691
- 15 Rebbeck TR, Troxel AB, Norman S et al. A retrospective case-control study of the use of hormone-related supplements and association with breast cancer. Int J Cancer 2007; 120: 1523-1528
- 16 Zepelin HH, Meden H, Kostev K et al. Isopropanolic black cohosh extract and recurrence-free survival after breast cancer. Int J Clin Pharmacol 2007; 45: 143-154
- 17 Community herbal monograph on Cimicifuga racemosa (L.) Nutt., rhizoma, EMA/HMPC/600717/2007 Corr, 2010.
- 18 Reed SD, Newton KM, LaCroix AZ et al. Vaginal, endometrial, and reproductive hormone findings: randomized, placebo-controlled trial of black cohosh, multibotanical herbs, and dietary soy for vasomotor symptoms: the Herbal Alternatives for Menopause (HALT) study. Menopause 2008; 15: 51-58
- 19 Borrelli F, Ernst E. Black cohosh (Cimicifuga racemosa): a systematic review of adverse events. Am J Obstet Gynecol 2008; 199: 455-466
- 20 Mahady GB, Low Dog T, Barrett ML et al. United States Pharmacopeia review of the black cohosh case reports of hepatotoxicity. Menopause 2008; 15 (4 Pt 1) 628-638
- 21 Heger M, Ventskovskiy BM, Borzenko I et al. Efficacy and safety of a special extract of Rheum rhaponticum (ERr 731) in perimenopausal women with climacteric complaints: a 12-week randomized, double-blind, placebo-controlled trial. Menopause 2006; 13: 744
- 22 Wober J, Möller F, Richter T et al. Activation of estrogen receptor-beta by a special extract of Rheum rhaponticum (ERr 731), its aglycones and structurally related compounds. J Steroid Biochem Mol Biol 2007; 107: 191-201
- 23 Hasper I, Ventskovskiy BM, Rettenberger R et al. Long-term efficacy and safety of the special extract ERr 731 of Rheum rhaponticum in perimenopausal women with menopausal symptoms. Menopause 2009; 16: 117-131
- 24 NAMS. Treatment of menopause-associated vasomotor symptoms: position statement of The North American Menopause Society. Menopause 2004; 11: 11-33
- 25 Wong VC, Lim CE, Luo X et al. Current alternative and complementary therapies used in menopause. Gynecol Endocrinol 2009; 25: 166-174
- 26 Winther K, Rein E, Hedman C. Femal, a herbal remedy made from pollen extracts, reduces hot flushes and improves quality of life in menopausal women: a randomized, placebo-controlled, parallel study. Climacteric 2005; 8: 162-170
- 27 Nedrow A, Miller J, Walker M et al. Complementary and alternative therapies for the management of menopause-related symptoms: a systematic evidence review. Arch Intern Med 2006; 166: 1453-1465
- 28 Ziaei S, Kazemnejad A, Zareai M. The effect of vitamin E on hot flashes in menopausal women. Gynecol Obstet Invest 2007; 64: 204-207
- 29 Pachman DR, Jones JM, Loprinzi JL. Management of menopause-associated vasomotor symptoms: Current treatment options, challenges and future directions. Int J Womens Health 2010; 2: 123-135
- 30 Pitkin J. Alternative and complementary therapies for the menopause. Menopause Int 2012; 18: 20-27
- 31 Loprinzi CL, Pisansky TM, Fonseca R et al. Pilot evaluation of venlafaxine hydrochloride for the therapy of hot flashes in cancer survivors. J Clin Oncol 1998; 16: 2377-2381
- 32 Loprinzi CL, Kugler JW, Sloan JA et al. Venlafaxine in management of hot flashes in survivors of breast cancer: a randomised controlled trial. Lancet 2000; 356: 2059-2063
- 33 Evans ML, Pritts E, Vittinghoff E et al. Management of postmenopausal hot flushes with venlafaxine hydrochloride: a randomized, controlled trial. Obstet Gynecol 2005; 105: 161-166
- 34 Stearns V, Slack R, Greep N et al. Paroxetine is an effective treatment for hot flashes: results from a prospective randomized clinical trial. J Clin Oncol 2005; 23: 6919-6930
- 35 Loprinzi CL, Sloan JA, Perez EA et al. Phase III evaluation of fluoxetine for treatment of hot flashes. J Clin Oncol 2002; 20: 1578-1583
- 36 Barton DL, Loprinzi CL, Novotny P et al. Pilot evaluation of Citalopram for the relief of hot flashes. J Support Oncol 2003; 1: 47-51
- 37 Loprinzi CL, Flynn PJ, Carpenter LA et al. Pilot evaluation of citalopram for the treatment of hot flashes in women with inadequate benefit from venlafaxine. J Palliat Med 2005; 8: 924-930
- 38 Kalay AE, Demir B, Haberal A et al. Efficacy of citalopram on climacteric symptoms. Menopause 2007; 14: 223-229
- 39 Jin Y, Desta Z, Stearns V et al. CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment. J Natl Cancer Inst 2005; 97: 30-39
- 40 Loprinzi L, Barton DL, Sloan JA et al. Pilot evaluation of gabapentin for treating hot flashes. Mayo Clin Proc 2002; 77: 1159-1163
- 41 Guttuso jr. T, Kurlan R, McDermott MP et al. Gabapentinʼs effects on hot flashes in postmenopausal women: a randomized controlled trial. Obstet Gynecol 2003; 101: 337-345
- 42 Pandya KJ, Morrow GR, Roscoe JA et al. Gabapentin for hot flashes in 420 women with breast cancer: a randomised double-blind placebo-controlled trial. Lancet 2005; 366: 818-824
- 43 Lavigne JE, Heckler C, Mathews JL et al. A randomized, controlled, double-blinded clinical trial of gabapentin 300 versus 900 mg versus placebo for anxiety symptoms in breast cancer survivors. Breast Cancer Res Treat 2012; 136: 479-486
- 44 Guttuso jr. T. Effective and clinically meaningful non-hormonal hot flash therapies. Maturitas 2012; 72: 6-12
- 45 Nelson HD, Vesco KK, Haney E et al. Nonhormonal therapies for menopausal hot flashes. Systematic review and meta-analysis. JAMA 2006; 295: 2057-2071
- 46 Mueck AO, Rabe T, Kiesel L. Hormonersatztherapie bei Patientinnen nach Mammakarzinom. J Reproduktionsmed Endokrinol 2006; 3: 145-154
- 47 Baumelou A, Liu B, Wang XY et al. Perspectives in clinical research of acupuncture on menopausal symptoms. Chin J Integr Med 2011; 17: 893-897