Endoscopy 2018; 50(02): v7
DOI: 10.1055/s-0043-123975
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© Georg Thieme Verlag KG Stuttgart · New York

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Publication Date:
29 January 2018 (online)

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Impact of preprocedure simethicone on adenoma detection rate during colonoscopy: a multicenter, endoscopist-blinded randomized controlled trialEndoscopy 2018; 50(02): 128-136
DOI: 10.1055/s-0043-119213

    Yu Bai et al. Impact of preprocedure simethicone on adenoma detection rate during colonoscopy: a multicenter, endoscopist-blinded randomized controlled trial

    This randomized controlled trial involving 583 Chinese patients examined whether adding oral simethicone to bowel preparation with polyethylene glycol (PEG) could improve the adenoma detection rate. When compared with PEG alone, PEG plus simethicone improved the adenoma detection rate (21 % vs. 14 %) and mean number of adenomas detected (2.2 vs. 1.6). The benefit was maintained after adjusting for bowel preparation quality, which was better in the intervention group.

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