Download PDF
Synfacts 2020; 16(03): 0358
DOI: 10.1055/s-0039-1691671
Peptide Chemistry
© Georg Thieme Verlag Stuttgart · New York

Heterogeneous Catalysis for Amide Bond Formation

Contributor(s):
Hisashi Yamamoto
,
Wataru Muramatsu
de Azambuja F, Parac-Vogt TN. * KU Leuven, Belgium
Water-Tolerant and Atom Economical Amide Bond Formation by Metal-Substituted Polyoxometalate Catalysts.

ACS Catal. 2019;
9: 10245-10252
CrossrefSearch in Google Scholar
Further Information

Publication History

Publication Date:
18 February 2020 (online)

 
 PDF Download Permissions and Reprints

Key words

polyoxometalates - zirconium catalysis - Lewis acids - amides - green chemistry - atom-economic synthesis

Significance

The development of recyclable catalysts is an ongoing challenge in chemical production. The authors have developed new recyclable and ecofriendly catalysts for amide bond formation.


#

Comment

This inter- and intramolecular amidation reaction using recyclable and water-tolerant catalysts provides the corresponding amides, including cyclic peptides, in good to high yields.


#
#


   Permissions and Reprints